What is Psilocybin (Magic Mushrooms)?
Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) and psilocin are chemical compounds obtained from certain types of dried or fresh hallucinogenic mushrooms found in Mexico, South America and the southern and northwest regions of the United States. However, Psilocybin is classified as an indole-alkylamine (tryptamine). These compounds have similar structure to lysergic acid diethylamide (LSD), and abused for their hallucinogenic and euphoric effects to produce a “trip”. Hallucinogenic (psychedelic) effects are probably due to action on central nervous system serotonin (5-HT) receptors.
Over 180 species of mushrooms that contain the chemicals psilocybin or psilocin. Like the peyote (mescaline), hallucinogenic mushrooms have been used in native or religious rites for centuries. Both psilocybin and psilocin can also be produced synthetically in the lab. There have been reports that psilocybin bought on the streets can actually be other species of mushrooms laced with LSD.
Methods of Psilocybin Use
“Magic Mushrooms” have long, slender stems. It may appear white or greyish topped by caps with dark gills on the underside. Dried mushrooms are usually a reddish rust brown color with isolated areas of off-white. Mushrooms are ingested orally and may be made into a tea or mixed into other foods. The mushrooms may be used as fresh or dried product. Psilocybin has a bitter, unpalatable taste.
A “bad trip”, or a unpleasant or even terrifying experience, may occur with any dose of psilocybin. In general, dried mushrooms contain about 0.2% to 0.4% psilocybin and only trace amounts of psilocin. The typical dose of psilocybin used for recreational purposes varies. With peak effects occurring in 1 to 2 hours, and lasting for about six hours.
Dose and effects can vary considerably depending upon mushroom type, method of preparation, and tolerance of the individual. It can therefore be difficult to determine the exact species of mushroom or how much hallucinogen each mushroom contains. Initial smaller doses and a longer period of time to determine the effects may be a safer option if you choose to use psilocybin for recreational purposes.
Effects of ‘Magic Mushroom’ Use
Psilocybin effects are similar to those of other hallucinogens, such as mescaline from peyote or LSD. The psychological reaction to psilocybin use include visual and auditory hallucinations and an inability to discern fantasy from reality. As a result, Panic reactions and psychosis also may occur, particularly if large doses of psilocybin are ingested.
Hallucinogens that interfere with the action of the brain chemical serotonin may alter:
Physical effects of psychedelic mushrooms may include a feeling of nausea, vomiting, muscle weakness, confusion, and a lack of coordination. Combined use with other substances, such as alcohol and marijuana can heighten, or worsen all of these effects.
Above all, other effects of hallucinogenic drugs can include:
intensified feelings and sensory experiences
changes in sense of time (for example, time passing by slowly)
increased blood pressure, breathing rate, or body temperature
loss of appetite
mixed senses (such as “seeing” sounds or “hearing” colors)
feelings of relaxation or detachment from self/environment
paranoia – extreme and unreasonable distrust of others
psychosis – disordered thinking detached from reality